STOICHIOMETRIC SYNTHESIS OF METABOLIC PATHWAYS

A vector-matrix approach to the theoretical design of metabolic pathways converting chemical compounds, viz., preset substrates, into desirable products is described.It is a mathematical basis for computer-aided generation of alternative biochemical reaction sets executing the given substrate-product conversion.The pathways are retrieved from the u

Transcriptional gene silencing (TGS) can serve as an innate immunity against invading DNA viruses throughout Eukaryotes.Geminivirus code for TrAP protein to suppress the TGS pathway.Here, we identified an diet frostie root beer Arabidopsis H3K9me2 histone methyltransferase, Su(var)3-9 homolog 4/Kryptonite (SUVH4/KYP), as a bona fide cellular target